Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents With HIV

Antiretroviral therapy (ART) for the treatment of HIV infection has improved steadily since the advent of potent combination therapy in 1996. ART has dramatically reduced HIV-associated morbidity and mortality and has transformed HIV infection into a manageable chronic condition, with life expectancy approaching that for people without HIV.1,2 ART is also highly effective at preventing sexual transmission of HIV in patients who have adequately suppressed viral loads.3-5 Lack of viral load suppression is mostly due to undiagnosed HIV infection and failure to link or retain patients with HIV in care.

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